Holistic care refers to healthcare that tries to integrate the whole person rather than symptom based `comprehensive` care that tends to look at one symptom at a time. Persons with chronic disease often experience an involvement of multiple body systems. A comprehensive care approach to patient care is often used with the belief that a health care team will ensure that a patient’s needs will be covered. Instead, this approach is reductionist in practice and leads to fragmentation of care, and the difficult patients often slip through the cracks of the health care system. However, a holistic theory-based approach puts a patient’s perceived needs first and offers care not only for the body but also for the human spirit.